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CBD in cosmetics - how well does cannabidiol affect our skin?

the biggest appeal features - no wonder we're ready to invest a lot in effective skin care products. Care products that contain CBD extracts such as CBD oil are currently emerging as a new trend in the cosmetics market. Are you just a marketing gimmick? On the contrary, medical studies hope that cannabidiol could help with skin problems: Which cosmetics with CBD are there?Almost the entire spectrum of personal care products you will also get today with CBD offset: from shampoo, on the lip balm to creams and ointments. The latter are advantageous because they are not washed out or washed off like soap, but let the valuable ingredients of the contained CBD extract penetrate into the skin. In addition to cannabidiol, ointments and creams naturally also contain ingredients which give the respective product its consistency and scent. Make sure that natural fats such as shea butter, mango butter or cocoa butter are used. They moisturize the skin and have a moisturizing effect. As fragrances, producers of high-quality products use natural essential oils, which in turn supply valuable terpenes. Quality products can be recognized by the fact that a CBD full spectrum extract forms the basis and neither artificial preservatives nor fragrances are processed. Vitamin E, on the other hand, is a natural preservative in CBD cosmetics that protects both our products and our skin from oxidation damage. Is CBD absorbed through the skin?Like all cannabinoids, CBD is a lipophilic substance that dissolves well in oils and fats. Therefore, it also combines with the human skin fat and is absorbed through the epidermis in the metabolism. Studies show that skin gives CBD 10 times more permeability than THC.  But can CBD also influence the organism through this passage? Preclinical experiments with animals show that CBD also has high efficacy via the transdermal route. For example, a gel containing cannabidiol in arthritic rats reduced joint swelling and pain and improved their mobility. In another experiment, CBD mitigated an addictive behavior induced by stress as an ointment in the experimental animals.  Also, pharmaceutical companies want to use the transdermal uptake of CBD in their products in the future: The Canadian manufacturer Cannabis Science announced to develop a CBD patch that will help patients with fibromyalgia and neuropathic pain in the future. How does CBD affect the skin? Because CBD is anti-inflammatory and immunoregulatory, it could primarily help people who suffer from inflammatory skin conditions. Researchers see above all possibilities in the treatment of acne. Because of the activation of the vanilloid receptor type 4 CBD demonstrably inhibits the activity of the sebaceous cells in the sebaceous glands, called sebocytes.  In addition, it also has an inhibitory effect on cells of the epidermis, which are responsible for the formation of the horny layer. This could help people with psoriasis, whose complaints are caused by excessive activity of horn-forming keratinocytes. Finally, patients with severe skin diseases already benefit from CBD in practice. Case reports of sufferers of rare skin conditions, such as epidermolysis bullosa, show that their symptoms significantly decreased with cannabidiol therapy. Itching, sore and scarring, blisters and the limitations of mobility decreased so much that some patients could even do without opioid analgesics.  Source: CBD in Kosmetik – wie gut wirkt Cannabidiol auf unsere Haut? Apr 25,2019. Dostupné z: https://fivebloom.de/blogs/cbd-news/cbd-kosmetik Source photo: https://pixabay.com/cs/

CBD in allergies - can cannabidiol soothe the immune system?

Some of them are happy when trees and flowers are blooming in spring, while others would rather escape to the North Pole. In particular, hay fever sufferers can hardly enjoy the warm season, because they bring along with the pollen Schniefnasen, watery eyes and sneezing attacks. But also food allergies; House dust allergies and incompatibilities with chemicals make everyday life difficult for those affected. What happens in the body during allergies, such as CBD oil could increase the well-being of allergy sufferers, you will find out here: What are allergies?In an allergy, the human organism reacts to individual substances of its environment (allergens) with a strong immune response. In this case, pro-inflammatory substances such as e.g. Released histamine that cause typical discomfort. The physical symptoms then express themselves in:red and irritated eyesirritated nasal mucosahay feverSneezeto coughallergic asthmadigestive problemsSkin irritation and rashEczema and eczemaFor example, allergens are taken via the respiratory tract, as is the case with widespread hay fever. According to recent surveys, about 14.5 percent of all Germans suffer from respiratory ailments during their heyday. In addition, allergens can also enter the body through food or through direct skin contact. What is the usual therapy for allergies?Here are two approaches: The first is based on drugs that reduce the production of the inflammatory histamine in the body, so-called antihistamines. These preparations are effective and are available over the counter. However, they are sometimes associated with unpleasant side effects, especially with severe fatigue. In addition, there is the possibility of hyposensitization for allergy sufferers. In this case, the person concerned receives low-dose injections of the corresponding allergen, in order to slowly get the body used to the substance. How does CBD affect our immune system? The human endocannabinoid system and the immune system are closely related. After all, CB2 receptors to which cannabinode can bind are located on the important cells of the immune system, for example the T cells. Here, cannabinoids can regulate how many pro-inflammatory signaling substances are released during an immune response. Researchers in the animal model of asthma demonstrated that this regulatory effect can have a beneficial effect on allergic reactions. Treatment with CBD was able to significantly reduce the pro-inflammatory signaling, various interleukins and tumor necrosis factor alpha in the lung tissue of the experimental animals. The authors of the study are in favor of CBD as a potential future therapeutic for the inflammatory processes in asthma. Surveys in dermatology, however, see opportunities in CBD to treat atopic dermatitis and contact allergies. Finally, scientists in the animal model of arthritis have observed that cannabidiol can also regulate autoimmune responses by reducing the presence of proinflammatory signaling in the synovial fluid.  Which CBD products are suitable for an allergy?Dietary supplements with CBD are freely available in Germany and do not bring the risk of side effects. Unlike with the use of antihistamines, allergy sufferers do not have to worry about drowsiness. It is known from scientific experiments that CBD is absorbed well via the oral mucosa and via the transdermal route. In principle, allergy sufferers can therefore use CBD oil or CBD balm. When products are applied to the skin, it is important that there are no ingredients that can cause allergies. Ideal are CBD balms, which contain only natural fats such as shea butter or mango butter and do without chemical preservatives and fragrances. Even less risk of allergies exists in CBD oils based on MCT oils. They are dripped under the tongue on the oral mucosa to ensure optimal absorption of the ingredients in the organism. Beginners should begin with a 5 to 10 percent CBD oil picking and a dosage of 3 drops twice a day. Source: CBD bei Allergien – kann Cannabidiol das Immunsystem beruhigen?  May 2, 2019. Dostupné z: https://fivebloom.de/blogs/cbd-news/cbd-bei-allergien-oder-heuschnupfen Source photo: https://pixabay.com/cs/

Regular pain: CBD helps

CBD relaxes and relieves crampsWhile most of the average 28-day cycle is relatively calm and normal, the uterine muscles begin to contract just before the menstrual period. These contractions interrupt blood flow in the abdomen. It is precisely this interruption that causes more pain in one woman and less pain in the other. Happy are those who do not suffer at all. In some girls and women, however, the pain is so unbearable that they therefore even fail in everyday life, so must report to the employer sick or can not go to sports. In Germany, therefore, many patients resort to analgesics such as ibuprofen or acetaminophen. Others prefer to take antispasmodic drugs from the pharmacy. However, this is more of a permanent solution with two eyes closed, as this type of medication has negative effects on the body. For example, they strain the kidneys when taken regularly. Some pain sufferers now stick electrodes instead to the skin. By light surges, the muscles should relax and provide relief. While some swear by it, others complain about the annoying feeling of having to walk around the bikini area with electrode stickers, where one can not move quite as freely during the days anyway. Often, young women are prescribed the pill to prevent the unpleasant side effects of menstruation. However, it is artificially intervened in the hormone balance to prevent ovulation. The cannabinoid CBD is according to the current state of research free of side effects. It naturally acts on the human endocannabinoid system. This expands throughout the body and even produces various cannabinoids to keep the immune system intact. However, this system is prone to disorders such as illness and stress - the latter is also caused by pain. By administering CBD in the form of oil or capsules, the inner balance can be restored. CBD has a relaxing, anti-spasmodic and anti-inflammatory effect. For menstrual problems, it is therefore a good treatment option. Since it contains virtually no THC and therefore does not have an intoxicating effect, women who suffer from period pain can obtain CBD legally and without a prescription. Different types of menstrual pain and their causes The female cycle is determined by different hormones. The goal is to prepare the body for possible reproduction. Therefore, the uterine lining builds up in the first half of the cycle. It is well supplied with blood and thick or short: ready for the implantation of the fertilized egg. However, if there is no fertilization and thus no pregnancy, the mucosa dissolves in the second half of the cycle after ovulation from the uterus. The excretion takes place during the period. After the menstrual period, the circulation starts again, so the menstrual pain occurs every month again. Generally, a distinction is made between primary and secondary menstrual pain. The primary menstrual pain falls into the category of "natural", which is pain that occurs during the menstrual period, without any pathological change in the female body. The women who suffer from primary periodic pain have been fighting this problem since puberty. Secondary menstrual pain primarily affects older women and is mostly due to illness. Changes in the female reproductive system often cause painful days. Such changes include, for example, endometriosis (small, benign growths in the abdomen), uterine infections, and ovarian cysts. Frequently by these diseases not only the intensity of bleeding increases, but also pain. In general, there are various factors, besides malformations or diseases, which can aggravate menstrual pain. These include a low body weight, an irregular or longer than average cycle, the consumption of alcohol and nicotine, the prevention of pregnancy with the help of the spiral, stress or other psychological causes. Symptoms of menstrual painMany readers know her too well - the typical symptoms of menstrual cramps: cramping and tearing in the abdomen. The pain can follow at short intervals, be regular or prolonged, and can be up to the back. Often, digestion is also affected during the period, so some women suffer from diarrhea or nausea. Even headaches can be part of the discomfort. Anyone who is in constant pain and uncomfortable will eventually get into a bad mood. In addition, fatigue, fatigue and lower concentration or performance are added to this. Many women would therefore just like to lie in the hot tub or with a hot water bottle on the stomach on the couch and wait for the first two, so the worst days, pass as quickly as possible. Different forms of CBD for menstrual pain Not only hot baths and hot water bottles relax the cramped uterus, but also sex. But after a suitable partner is not always and everywhere available and women can not spend hours in the bathroom, it makes sense to relax the body in other ways. CBD has anti-spasmodic properties, reduces stress and relaxes, and therefore relieves menstrual pain. Already Queen Victoria's doctor, Sir Joshua Reynolds, knew about the beneficial effects of the cannabis plant and ordered the majesty a suitable cannabis tincture against her menstrual pain. Women in Asia and Africa have also been relying on natural pain relief from cannabis products for centuries. In our society, the use and research of cannabinoids has long been neglected by the illegalization of the hemp plant. However, countries such as the US and Canada are now turning around and the research and production of various cannabis products is evidently progressing inexorably. Europe is slowly catching up. The US actress Whoopi Goldberg has recognized the trend and together with the food manufacturer Maya Elisabeth sells medical cannabis products under the name "whoopi & maya", which are tailored to women with regular pains. In addition to cannabis tinctures and ointments, the ladies also offer a bath additive and chocolate with the corresponding active ingredients. In liberal California and the US state of Colorado, pain-stricken women enjoy the so-called cannabis tampons, which are marketed under the name of Foria Relief. Actually, this product is not really a tampon, but a suppository, which is introduced before using a tampon. Within 15 to 30 minutes, the suppository dissolves, so that the active ingredients are absorbed by the vaginal mucosa. In Germany, the suppositories are not yet available because they contain besides ten milligrams of legal CBD also 60 milligrams of psychoactive THC. Many women reported having a relaxing effect and pain relief after about eight minutes. The THC can be detected by the usual drug tests in the body. Medically sound studies on Foria Relief are pending. We also have medical cannabis products on prescription from the pharmacy. These are mainly used in palliative medicine. In menstrual pain, it would be extremely difficult to find a doctor and a health insurance company who would participate in a prescription. The legal alternative is CBD. In the form of oil, you can either take cannabidiol orally or drip one or two drops on a tampon to make it easier to get it right where it's needed. Instructions for buying CBD productsTo minimize the unwanted ingestion of any pollutants, attention should be paid to the bio-seal when purchasing CBD products. Oils should contain at least 99 percent pure CBD. When manufacturing, it is important to keep an eye on ensuring that the products are as close as possible to the GMP (Good Manufacturing Practice for Medicines) and ISO standards so that they are of a certain quality. Court decision regarding cannabis use against menstrual painAt this point the readers should not be deprived of the court order of 4 January 2017 from Baden-Württemberg: A woman who regularly consumed cannabis for six to seven days a month - the intoxicating THC variant, not the pure CBD - wanted to deprive the driving license authority of their driving license. In an urgent procedure, however, the Freiburg administrative court ruled that the woman was allowed to keep her driver's license for the time being. The reasoning was that the person concerned would firstly have not combined consumption and driving, and secondly, they would not take cannabis regularly. Even if the consumption was monthly over several days, the woman did not take THC-containing products on the menstruation-free days and therefore did not fulfill the conditions necessary for a driving license withdrawal.The decision may be understood as a positive sign in the direction of cannabis for pain relief. Source: SOMMER, Kathryn. Regelschmerzen: CBD schafft Abhilfe. 21 Feb, 2018 Dostupné z: https://www.hanf-magazin.com/medizin/cannabinoide/cbd-in-der-medizin/regelschmerzen-cbd-schafft-abhilfe/ Source photo: https://pixabay.com/cs/

Cannabis for autistic children

MODI'IN IN ISRAEL - Noa Shulman, 17 years old, is one of those children who have already attracted attention as an ego-centrist in kindergarten and at school. She lives seemingly completely withdrawn in her very own universe and has a hard time communicating with the outside world: Noa suffers from autism.When Noa comes home from school, she is spoon fed by her mother, Yael - sweet potato puree mixed with a cannabis-derived oil. Noa is part of the first clinical trial in the world to demonstrate the benefits of medical marijuana in the treatment of adolescents with autism. The positive effect should be provenThis study could be the breakthrough, helping millions of sufferers and their parents help and alleviate symptoms. The study started in January of this year at the Shaare Zedek Medical Center in Jerusalem. 120 children and young adults aged 5 to 29 with mild and severe autistic features are participating in the study, which will end in 2018. The group is expected to take cannabis daily, planned twice twelve weeks, interrupted by a one-month break. Nobody smokes a joint though. An extract of cannabidiol, which is mixed in the ratio of 20 to 1 with olive oil, is administered.There has long been evidence that cannabidiol (CBD) helps children and adolescents such as Noa, as has no other treatment or medication. This study should prove that. In 1992, Israel was the first country in the world to approve the use of medical marijuana. Like Canada and the Netherlands, this medical program is supported by the state and paid by the government. Tamir Gedo, CEO of "Breath of Life Pharma *," who made the cannabis oil for study participants, said that a mother told him, "My child is talking uninterruptedly. ... He never said a word before. And he is twelve years old. "Of course, there are also external concerns about the study. Pediatricians from America fear damage to the participants' brains due to the early intake of cannabis. But Gedo sees it differently, other drugs such as opioids hurt the children much more. "These families have no other hope." In Germany, the number of autistic people is estimated at around 35,000. * "Breath of Life Pharma" (BOL Pharma) is led by an experienced team of medical experts, scientists and cannabis business experts who have vast experience in clinical trials, precision farming, agriculture and marketing of pharmaceutical and healthcare products. BOL Pharma also owns the largest cannabis plantation in Israel, which is used for medical purposes. Her specialties include immunology (multiple sclerosis, fibromyalgia), pain therapy (chronic pain, neurological pain), gastrointestinal diseases (IBD), rheumatology (osteoarthritis), dermatology (psoriasis, atopic dermatitis). Source: NESTLER, Julia. Cannabis für autistische Kinder. 5 Jun 2017. Dostupné z: https://www.hanf-magazin.com/medizin/cannabinoide/cbd-in-der-medizin/cannabis-fuer-autistische-kinder/ Source photo: https://pixabay.com/cs/