Výsledky vyhledávání pro dotaz disease:

Výsledky vyhledávání v sekci: blog

Whether acute or chronic - CBD relieves pain

Pain has many facesIn Germany, several million people live with chronic pain. The published numbers fluctuate. Ten to 25 percent of all Germans are exposed to regular pain - this corresponds to about eight to 20 million people. The statistics are therefore relatively inaccurate, because many pain patients do not go to the doctor with their suffering. Some are afraid of being laughed at, others have given up their fight because they have not gotten better after a long odyssey, yet others do not want to be permanently dependent on harmful medicines.The reasons for pain are so complex that they can not all be listed here. Medicine distinguishes between acute and chronic pain. Acute pain occurs suddenly and does not last very long. They are even useful because they signal to the body that something is wrong. Only then can the cause be identified and remedied. Chronic pain starts from a minimum of three to six months. They are no longer useful, but reduce the quality of life of the person affected. Frequently a chronic pain is caused by inflammation, tension, chronic illness or nerve damage. Even acute pain can be attributed to such causes. However, they are also often caused by injuries - both internal and external - or illnesses. If the cause of acute pain is not resolved quickly, there is a risk that acute pain will turn into chronic pain. In addition, strong, persistent pain sensitizes the body to further pain. The nerves react "exaggerated" in the episode, even if the cause of the initial pain has already been eliminated. Whether a pain becomes chronic or not depends, among other things, on the patient's disposition, family environment and mental state.CBD has been shown to be effective against pain in several studies. The Cannabinoid combats several causes of pain, rather than simply suppressing the feeling of pain, the latter also belongs to the repertoire of cannabidiol.CBD fights painIn tissue injury, CBD increases the concentration of anandamide in the body. This occurs through the interaction of the cannabinoid with the receptors of the human endocannabinoid system. Ananadamide is an endogenous endocannabinoid that is directly produced by the body, which directly affects the pain. The more anandamide in the organism or around the injured area, the better the pain relief. Ananadamide binds to the CB1 receptor (cannabinoid-binding receptor) and to the TRPV1 (a vanilloid) receptor, where it immediately combats the pain. This finding was made by scientists in China in 2010, when they performed experiments on mice.CBD helps against inflammationInflammation is often the cause of pain. Inflamed tissue increases the number of free radicals. These are dangerous for the body, as they have, among other things, the property of damaging cells. CBD is an antioxidant. In this function, it has a similar effect to vitamins A, C and E: they trap free radicals and thus render them harmless.In addition, CBD also has an anti-inflammatory effect per se. For example, a study by GWPharmaceuticals showed that CBD's properties can help fight inflammatory conditions in the intestinal tract, rheumatoid arthritis, diabetes and nausea.Researchers at the University of Mississippi found that CBD reduces oxidative stress and helps fight inflammation. Many other studies - such as those of the scientists of the National Institutes of Health in Bethesda (USA) - all led to the same result: Cannabidiol inhibits inflammation. In Bethesda, researchers also confirmed that CBD works effectively against neuropathic pain. Neuropathic pain is caused by dysfunction or nerve injury and can sometimes be very severe.CBD protects the nervesCannabidiol not only works against neuropathic pain, but has been shown to protect against the death of nerve cells - such as ischemic stroke, traumatic brain injury, multiple sclerosis, Huntington's disease and other chronic nervous disorders. The neuroprotective (nerve-protective) effect of CBD has been demonstrated both in living organisms and in test tubes. Apparently, anandamide and 2-AG (2-arachidonylglycerol, another endocannabinoid) play an important role. In a traumatic brain injury, substances are released that can lead to secondary brain damage. In 2002 Mechoulem et al. Annanadamide and 2-AG can inhibit the action of harmful substances. The endocannabinoid system together with the cannabinoids thus takes over a protective function here. As described above, CBD contributes to the proliferation of anandamide in the body and thus protects the nerves. CBD relaxes the body and works against stressWhile the cannabinoid THC works primarily on the psyche, CBD has a relaxing and regulating effect on the body. Cannabidiol has an anticonvulsant effect, which is why it is sometimes used to combat epilepsy. Tense muscles often cause pain such as back, head, menstrual and other pains. But also CBD has positive effects on the psyche: It can be used well for the treatment of depression and schizophrenia. But it also helps against insomnia and stress. Stress is the cause of many pain disorders. Anyone who manages to reduce his stress often notices an accompanying pain relief. CBD combats the causesIn addition to inflammation, stress, tension and nerve disorders, CBD can be used against many other diseases. To name just a few:sleep disordersBurnoutanxiety disordersepilepsyschizophreniaNausea and vomitingDependence on addictive substancesParkinsonCrohn's diseasearthritisdifferent cancersspasticityasthmaCBD not only combats the pain as symptoms of disease, but acts - as a variety of different studies have revealed - against the causes themselves. For this reason alone, cannabidiol is likely to be a healthy alternative to the synthetic drugs of the pharmaceutical giants in the long term. These usually only suppress the pain. For the fight against causes additional medicines must be taken. Most painkillers and most prescription medicines, which are not natural but man-made, are harmful to the liver and kidneys - especially if taken over a long period of time. CBD, on the other hand, does not have a great health-endangering side-effect because it comes from nature and is very similar to human cannabinoids. Unfortunately, CBD research is still in its infancy. There are first drugs based on CBD. Overall, however, the science knows too little about the exact modes of action of cannabidiol. Questions such as "What helps CBD?" Could already be clarified well. But on the "How exactly does CBD?" There are only insufficient results. In the future, CBD is likely to play a bigger role in medicine - the current state of knowledge suggests strongly. Even though there are only very few CBD drugs worldwide so far, every human being in this country has the opportunity to treat themselves with CBD oil and other CBD products. CBD is not prescription, therefore legally available. For safety, always consult a doctor who is familiar with CBD. Application and dosage vary from person to person. In principle, with a little patience, everyone will find the right dose for themselves, as long as he starts small and slowly increases it until the desired effect begins. This makes CBD a good supplement to conventional pain therapy. With a bit of luck, some pain patients can even replace their existing funds with CBD altogether. A trial (under medical supervision) would be worth it. Source: SOMMER, Kathrin. Ob akut oder chronisch – CBD lindert Schmerzen.  13 Apr 2018 Dostupné z: https://www.hanf-magazin.com/medizin/cannabinoide/cbd-in-der-medizin/ob-akut-oder-chronisch-cbd-lindert-schmerzen/ Source photo: https://pixabay.com/cs/

Endogenous cannabinoids

Our organism, a criminal?The production of cannabis or the intoxicating tetrahydrocannabinol is prohibited in Germany, with exceptions. Our body forms endogenous cannabinoids. The anandamide discovered in 1992 is very similar to the THC. Is our organism a criminal? Does the mother behave irresponsibly when giving birth to her child, although breast milk contains endogenous cannabinoids? These questions simply remain unanswered and continue to focus on endogenous cannabinoids. Every higher living organism has an endocannabinoid system in which there are endogenous cannabinoids and cannabinoid receptors. These cannabinoid receptors can also dock with exogenous cannabinoids that are formed outside the body. However, cannabinoids formed in the body are called "endogenous". Endogenous is used within, exogenously outside of the body and as terms also in other areas of medicine. In 1992, the first endogenous cannabinoid was discovered with "anandamide", meanwhile also "2-arachidonylglycerol", "2-arachidonylglyceryl ether" and "O-arachidonylethanolamide" were discovered. There may be dozens of other endogenous cannabinoids that our body produces itself. These are messengers that dock to the cannabinoid receptors and trigger a reaction. Exogenous and endogenous cannabinoidsAmong the exogenous cannabinoids there are once the phytocannabinoids and the synthetic or semi-synthetic / artificial cannabinoids. The endogenous cannabinoids are always natural products as a product within our body. Here, however, as an organism, there are no great possibilities to form less or more of these endogenous cannabinoids, e.g. to achieve a more pleasant way of working. In the case of exogenous cannabinoids, however, it is possible to take them in any amount, if they are available in any quantity. Since marijuana always contains several cannabinoids at the same time, it would hardly be possible for normal users to take more of one cannabinoid without also including the other contained cannabinoids. However, if today's world wants it, then all of this would be possible because the cannabis strains can be optimized for breeding goals. On the other hand, the active ingredients can be extracted from the flowers as pure substances and then dosed very precisely. The difference in the bodyWhen exogenous cannabinoids are taken, they are taken up by the body via the lungs, the intestine, or the mucous membranes and pass into the bloodstream. This reaches the whole body and thus the effect of the exogenous cannabinoids also unfolds throughout the body. An exception would be only the external application of skin disorders. Endogenous cannabinoids, on the other hand, are always released where they are supposed to work. In the same body region where these agents or messengers arise, there are the matching cannabinoid receptors. As long as there are no messenger substances or they do not dock, the reaction of the receptors will be off, so they are so long inactive. However, if they are to react, the messenger substances are released to trigger a very targeted and spatially limited response. Delta-9-THC and anandamide are very similar in their effect. This THC is the only phytocannabinoid, which has an intoxicating effect and triggers the high. If anandamide is released in the organism, then only regionally. However, if you were to administer anandamide from the outside, it would go through the blood in the whole body and would certainly also make high. The name Anandamid was after all derived from Ananda, which means "bliss" and comes from the Sanskrit. Nevertheless, it can develop a very good medical effect in various diseases when THC is supplied to the organism. For the medical effect often enough dosages that do not make high, so that an everyday life remains possible. Difference between healthy and sickIn a healthy person, enough endogenous cannabinoids are released in different situations for the body to function normally. After all, cannabinoids are crucially important as messengers in the cannabinoid system, in order to control many different conscious and unconscious functions. In a sick person, there may be a deficiency in this cannabinoid system either at one or in some places. However, there may also be an additional need due to the disease. In both situations, it makes sense to take the right exogenous cannabinoids in sufficient quantities. In addition, of course, also be teased for pleasure. Or you simply take precautionary or relaxation CBD as well as other non-intoxicating cannabinoids. The healthy person can not do so much wrong, or would then usually stop by themselves quickly. In sick people, however, the difference in the effect is greater, which cannabinoids are taken in which concentration. Individual cannabinoids can be counterproductive in some diseases. Thus, too much THC can aggravate psychotic disorders quickly, but very often can be treated very well with CBD. While one can not exert much influence on the endogenous cannabinoids, as they are secreted by themselves in the body, exogenous cannabinoids can be used to great effect. That's exactly where the chances are in cannabinoid medicine. Source: BRUNGERT, Robert. Endogene Cannabinoide, 7 march 2018. Dostupné z: https://www.hanf-magazin.com/medizin/cannabinoide/endogene-cannabinoide/ Source photo: https://pixabay.com/cs/ 

Does CBD help stomach and intestines? Cannabidiol and the digestive tract

A good gut feeling is not only important in the figurative sense: The fact that the digestive tract works smoothly is essential for general well-being. But there is a problem here: it is estimated that 29 percent of the European population experience recurring indigestion; A total of 400,000 patients in Germany suffer from inflammatory bowel disease. Could CBD oil help alleviate the symptoms here? Below you will learn how the endocannabinoid system interacts with the digestive tract and what recent studies on CBD have found in bowel disease: What makes a healthy digestive system?The health of our intestinal tract is not only our business, but also that of trillions of microorganisms. Their job is to help digestion, neutralize potential toxins, make vitamins and communicate with the immune system. If bacterial colonization in the intestine is disturbed by pathological conditions, chronic intestinal inflammation and even mental illness can be the result. Animal experiments have already shown how the change in the intestinal flora in mice results in increased anxiety and a tendency to depression. Also in patients with a post-traumatic stress disorder, changes were detected in the occurrence of special intestinal bacteria. No wonder then that our intestinal tract is also referred to by some scientists as the "gut brain". A gut feeling would therefore not be a vague feeling, but may be the result of the collective intelligence of trillions of intestinal bacteria. How do cannabinoids affect the intestine?The human endocannabinoid system also extends to our digestive organs. CB1 receptors are located in the stomach and intestine, where they allow (endo) cannabinoids to control appetite and saturation. In addition, they affect motility, i. the movements that maneuver our food through the digestive tract. Finally, the anti-inflammatory potential of some cannabinoids could have a positive effect on the intestinal mucosa and correlate with a healthy intestinal flora: In which intestinal diseases could CBD support well-being?A well-known chronic intestinal disease is irritable bowel syndrome. Physicians are still uncertain about his cause - but his symptoms severely affect the quality of life of those affected: diarrhea, flatulence, cramps and constipation are the result. Stress, intolerance to certain foods or taking hormone supplements such as the "pill" can cause relapses. Scientists are currently working on a theory that explains chronic pain in irritable bowel syndrome, which can hardly be attributed to external factors, by a lack of endocannabinoids (Clinical Endocannabinoid Deficiency Syndrome). [2] Here, an intake of herbal cannabinoids such as CBD could possibly have a positive effect and reduce painful discomfort. This thesis is supported by numerous reports of irritable bowel patients, whose quality of life CBD could increase. CBD and inflammatory bowel disease and CBDIn inflammatory bowel diseases such as Crohn's disease and ulcerative colitis, there are inflammations of the intestinal tract, which cause bumpy severe discomfort. Doctors suspect the triggers in an autoimmune reaction. The fact that cannabis preparations can alleviate the symptoms is well known. [3] In addition, a 2011 study examined the mechanisms by which CBD, as a single substance, could exert a positive influence on inflammatory processes in the gut: it has been shown to control the activation of enteric glial cells. In turn, these cells increasingly release growth factors and inflammatory signaling substances (cytokines). In excess they can cause inflammation. The modulating capabilities of CBD could mitigate these processes.  Source: Hilft CBD Magen und Darm? Cannabidiol und der Verdauungstrakt. Apr,22 2019. Dostupné z: https://fivebloom.de/blogs/cbd-news/hilft-cbd-magen-und-darm Source photo: https://pixabay.com/cs/

The endocannabinoid system: How THC works in the body

The beginningsModern cannabinoid research, which began about 50 years ago, was initially initiated to understand the effect of an illicit drug. After the chemistry of the plant and the pharmacological and psychological effects of THC were at least partially understood in the 60s and 70s, the field of research changed. From the mid-80s, research into the mode of action of THC and other cannabinoids in the hemp plant in the body and thus the discovery of the endocannabinoid system began. It soon became clear that this body's regulatory system is involved in many bodily functions.In 1964, the complete elucidation of the chemical structure of the delta-9-THC of the hemp plant was achieved. Approximately 30 years later, the first endogenous cannabinoids were discovered, arachidonoylethanolamide (anandamide, AEA) in 1992, and arachidonoylglycerol (2-AG) in 1995. Since then, research on the effects of endocannabinoids on human health and disease has become more widespread.Endocannabinoid receptorsIn 1987, an American research group was able to show that there are specific binding sites in the brain for THC. Their distribution in the brain is consistent with the pharmacological properties of THC and other (synthetic) cannabinoids that cause psychic effects. In 1990, it was finally possible to decode the chemical structure of the first cannabinoid receptor in the brain. A short time later, a second cannabinoid receptor was detected in the spleen.The cannabinoid-1 receptorOriginally it had been thought that the CB1 receptor (cannabinoid-1 receptor) was found only in the central nervous system, so it was considered a brain cannabinoid receptor. However, it occurs in many organs. The CB1 receptor is one of the most common receptors in the brain. The highest concentrations are found, among others, in the basal ganglia of the brain, which play a role in the coordination of movements, or in the hippocampus, which is important for the conversion of short-term information into long-term memory contents or for spatial orientation. CB1 receptors are found in many regions that play an important role in sensory perception (taste, smell, touch, hearing), mental performance, and motivation. For example, when CB1 receptors in the brain are activated by THC, sensory perception increases. In this way, the taste and smell of food and listening to music intensifies.In contrast, there are no CB1 receptors in the brainstem responsible, inter alia, for the control of respiration and the cardiovascular system. Today it is assumed that there are no deaths from overdose of cannabis or THC in healthy persons, because the functions of the brainstem can not be significantly affected by such an overdose.The protective function of the CB1 receptorCannabinoid 1 receptors are located at the end of nerve cells, where a signal is passed through the gap between two nerve cells from one nerve cell to another. The most important function of the CB1 receptors in the nervous system is the inhibition of excessive signal transmission by messenger substances in the brain, so-called neurotransmitters. Activation of CB1 receptors inhibits overactivity of all neurotransmitters in the brain (glutamate, serotonin, dopamine, norepinephrine, etc.). Thus, the endocannabinoid system has multiple protective functions against over-excitement in the central nervous system and helps to balance the activity of the brain. This explains the broad spectrum of action of THC or cannabis. When THC binds to CB1 receptors, too much activity is inhibited in the pain control circuits of the brain, thereby relieving pain. If neurotransmitter activity is too high in regions responsible for nausea and vomiting, activation of the CB1 receptor may reduce this increased activity. By similar mechanisms, muscle spasticity, epileptic seizures, anxiety disorders, obsessive-compulsive disorder, hyperactivity and other disease symptoms are attenuated by activation of the endocannabinoid system.The cannabinoid 2 receptorOriginally it was thought that CB2 receptors only occur in the immune system outside the brain. However, they were eventually detected throughout the central nervous system, especially in microglial cells, albeit at a lower concentration than CB1 receptors. Microglial cells are crucial for brain immune defense.The body of humans and other mammals has a highly developed immune system that protects it from attack by viruses, bacteria and other potentially harmful external influences and aims to prevent, mitigate and repair the damage. The endocannabinoid system is part of this protective mechanism via its CB2 receptors.Endogenous cannabinoidsThe discovery of cannabinoid receptors suggested that there are endogenous substances that bind to these receptors. In fact, such an endocannabinoid was first detected in 1992. Its discoverers called it anandamide from the Sanskrit word "Ananda" for bliss and "amide" because of its chemical structure. In 1995, a second endocannabinoid, 2-AG (2-arachidonoylglycerol) was discovered. These two endocannabinoids are best researched so far. Today it is assumed that about 200 substances that resemble the discovered endocannabinoids in their chemical structure.Unlike most messenger substances (neurotransmitters) in the brain, they are not produced by the nerve cell, which transmits a signal to another nerve cell, but by the nerve cell that receives the signal. If the signal, ie the concentration of the neurotransmitters, is too large, endocannabinoids are increasingly formed which, via the activation of CB1 receptors, reduce this excessive neurotransmitter activity.Different endocannabinoids can bind not only to cannabinoid receptors, but also to a putative CB3 receptor, the GPR55 receptor, vanilloid receptors, and other receptors.Proteins for the formation and degradation of end cannabinoidsThe proteins responsible for the synthesis of endocannabinoids have so-called N-acyltransferase (NAT), N-acylphosphatidylethanolamine-specific phospholipase (NAPE-PLD) or diaclglycirollipase (DAGL). The most important protein for the degradation of anandamide is fatty acid amide hydrolase (FAAH) and for the degradation of 2-AG monoacylglycerol lipase (MAGL).Functions of the endocannabinoid system in the brainThe endocannabinoid system plays a role in the brain in anxiety and depression, in the regeneration of nerve cells, and it affects the reward system of the brain. It affects our mental capacity, ability to learn and memory. In this context, the eradication of unpleasant experiences by the endocannabinoid system is utilized in the treatment of post-traumatic stress disorder. The effects of endocannabinoids in the brain are mainly mediated via CB1 receptors, but also in part via CB2 receptors on glial cells.Many studies show that activators of the CB1 receptor, such as THC, affect short-term memory. This effect can be prevented by high doses of CBD.Interestingly, however, memory loss could be reduced with age by activating the endocannabinoid system. For example, mice lacking CB1 receptors showed accelerated age-related mental performance deficits. They also lost important nerve cells in the hippocampus, which was accompanied by inflammation of the nerve cells. These findings suggest that CB1 receptors in the hippocampus may protect against age-related decline in mental performance.conclusionThe endocannabinoid system, with its endocannabinoids, cannabinoid receptors, and proteins responsible for the formation and degradation of endocannabinoids such as anandamide and 2-AG, has central biological functions in the central nervous system and in many other organs. Disruptions to the normal functioning of this system can lead to corresponding disorders of organ function. In diseases, a specific effect on the endocannabinoid system may be useful, for example, by inhibiting the degradation of endocannabinoids or by the administration of herbal cannabinoids such as THC.There is also evidence that certain diseases such as migraine, epilepsy or irritable bowel syndrome are associated with reduced activity of the endocannabinoid system. One speaks of Endocannabinoidmangel illnesses. The ingestion of plant cannabinoids might then compensate for this decreased activity. Source: GROTENHERMEN, Dr. Franjo. Das Endocannabinoidsystem: Wie THC seine Wirkung im Körper ausübt.15 Aug, 2016,Dostupné z: https://www.hanf-magazin.com/medizin/cannabinoide/thc/das-endocannabinoidsystem-wie-thc-seine-wirkung-im-koerper-ausuebt Source photo: https://pixabay.com/cs/ 

Cannabis products for external use

We now know that the use of cannabis has health benefits. We can treat bowel disease with cannabis, fight colon cancer or relieve spasmodic symptoms. In addition, the effect of cannabis is also applicable to a great many other ailments, but the effects have not been completely investigated. Whether one eventually smokes or otherwise consumes the grass is up to the consumer.If you do not want to smoke, you can inject it through the skin, in the form of oil, through the food, or in finished foods. The possibilities are more or less open to us. A first step has already been taken with the legalization by prescription, even if it is only really recognized and serious diseases. The normal migraine patient will hardly get legal cannabis. That's a pity, but maybe that will change. Today, however, we are enriching ourselves with yet another effect of cannabis, namely the positive effects on our skin. The products are largely legally available.Effectiveness of THC and CBD confirmedClinical trials and numerous laboratory tests have now confirmed the efficacy of cannabis ingredients. It was investigated to what extent cannabis products can help against skin redness, inflammation, psoriasis, open wounds, acne or other skin diseases. Of course, the cannabis does not need to be smoked, but can be purchased legally in lotions, balms, oils or patches. We are looking forward to a product test in this regard and hope to be able to say more about exact products soon.Actually, people knew back in antiquity that cannabis and certain plant components help against skin diseases. For this reason, cannabis was mixed with other plants, herbs or animal extracts and prepared ointments. In today's laboratory tests, the effect was confirmed, because the cannabinoids increase the biochemical defenses of the skin. Unfortunately, we can not say much about exactly how cannabinoids do this and stimulate the healing process, because unfortunately research is not yet far enough. But the fact is that it helps and acts against a disease infestation of the skin.Acne and skin irritations - effects and resultsCannabinoids can reduce and even completely combat inflammation in the skin's sebaceous glands. Skin glands ensure that the skin is coated with sufficient natural fats. If the glands produce too much sebum, skin disorders or acne often occur. Cannabinoids have been proven to help against acne, eczema and other skin disorders. And again it was the mice that proved these theories. However, it is not just the cannabinoids that are good for our skin. The extracts of cannabis seeds, for example, reduced skin redness of subjects. These seeds contain proteins, oils and antioxidants to help against pimples.Skin care products are experiencing an upswingCannabis-enriched lotions are increasingly being sold and more and more people are experiencing the beneficial effects. Balsams, oils, gels or transdermal patches containing CBD, THC or terpene can be purchased. The cannabis preparations contain various substances, so that the skin can absorb the essential ingredients well. For example, the creams contain certain herbs to actively ensure intake. The products can be applied directly to the inflamed area and locally controlled.Will not you get high on it?No, because the ointments do not reach the bloodstream or the nervous system, whereby no high-effect can be experienced. The contained cannabinoids can bind with the CB2 receptors and act on the peripheral level.-> If you like, you can make your own CBD ointment yourself. All you need is cutaways, stalks and a few small buds. These are enriched with coconut oil and beeswax. We will work out a more exact recipe and of course publish it. Dermatitis and psoriasis are the perfect areas of application and you will see fast results. But even with sore muscles or against arthritis and for other pain relief help the homemade ointments.Patients and doctors should go new waysThe experiences of physicians and patients are becoming more and more frequent and also various official studies are proving more and more the positive effects on different processes. Relieving skin problems could be a breakthrough for cannabis products. In the US, various cannabis products are already being used to relieve symptoms such as fibromyalgia, ALS, sunburn, open wounds or migraine. The modes of action are antibacterial and anti-inflammatory, the properties of cannabis there are widely recognized. What works there can not be wrong here, right?Found a new drug?Now another active substance is to be held responsible for the positive effects on our organism, namely the so-called CBG. An active ingredient that can help against acne and skin aging.Of course, we must point out here that cannabis is not a panacea and you should always discuss your treatment with a doctor. At least you could ask in advance if self treatment with various cannabis products makes sense. Source: DIRSCHL, Jenny. Cannabisprodukte zur äußeren Anwendung. 17 feb, 2017. Dostupné z: https://www.hanf-magazin.com/medizin/cannabinoide/thc/cannabisprodukte-zur-aeusseren-anwendung/Source photo: https://pixabay.com/cs/

Can cannabis protect the liver from alcohol damage?

This is a medical recommendation for the use of alcohol. By regularly exceeding this daily dose serious health consequences are threatened because alcohol is toxic to the liver cells. Excessive consumption causes the liver to become inflamed, tissue scarred, and dangerous cirrhosis can be the result, as well as high blood pressure, strokes, liver disease and liver cancer.Is the combination of alcohol and cannabis more dangerous than the individual substances?Recently, scientists from the University of Massachusetts Medical School and the INRS Armand-Frappier Research Center, led by Drs. Terence Bukong on the effects of long-term mixed cannabis and alcohol use on the liver. The 2018 study included studies in about 320,000 people who had a longer history of both substances. And although one would think that combined consumption would necessarily increase the negative consequences for the body, the results of the investigations show that it is surprisingly different in this case.Cannabinoids like CBD inhibit the cause of liver diseaseBukong and his team found that in people who consume both alcohol and cannabis, the risk of alcohol-related liver disease is lower. And the more cannabis people consume, the stronger this effect is. The researchers explain these amazing results with the anti-inflammatory effect that cannabis, and especially cannabidiol (CBD) has. Older studies suggest that cannabinoid receptors in the liver are able to prevent or treat liver disease. The activation of these receptors by cannabis reduces the inflammation of the liver cells at an early stage. This slows down the progressive damage caused by alcohol.The research on the mixed consumption of alcohol and cannabis goes into the next roundDr. However, Bukong warns against understanding the research findings as an invitation to excessive mixed drinking. Because many historical data were collected through interviews, there is no information on the quality and drug concentration of cannabis that the participants consumed at that time. So far, there are no clinical studies that have tracked the effects of mixed consumption virtually in real time. Bukong's research group is already working to find out which cannabinoids and combinations of cannabinoids have the best medical effect on liver disease.Coffee and cannabis prevent scarring in liver tissueDespite all precaution and caution, as a result of their research, researchers find that cannabis users are less likely to suffer from alcohol-related liver damage, the least to long-term consumers. Also good for preventing scarring in the tissues of the liver should be drinking two to three cups of black coffee per day. Why this is so, has not been explored until today. Source:KLAUS GLASMANN, Dieter. Kann Cannabis die Leber vor Alkohol-Schäden schützen? 28 Mai, 2019. Dostupné z: https://www.hanf-magazin.com/medizin/cannabismedizin-allgemein/kann-cannabis-die-leber-vor-alkohol-schaden-schuetzen/Source photo: https://pixabay.com/cs/