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Whether acute or chronic - CBD relieves pain

Pain has many facesIn Germany, several million people live with chronic pain. The published numbers fluctuate. Ten to 25 percent of all Germans are exposed to regular pain - this corresponds to about eight to 20 million people. The statistics are therefore relatively inaccurate, because many pain patients do not go to the doctor with their suffering. Some are afraid of being laughed at, others have given up their fight because they have not gotten better after a long odyssey, yet others do not want to be permanently dependent on harmful medicines.The reasons for pain are so complex that they can not all be listed here. Medicine distinguishes between acute and chronic pain. Acute pain occurs suddenly and does not last very long. They are even useful because they signal to the body that something is wrong. Only then can the cause be identified and remedied. Chronic pain starts from a minimum of three to six months. They are no longer useful, but reduce the quality of life of the person affected. Frequently a chronic pain is caused by inflammation, tension, chronic illness or nerve damage. Even acute pain can be attributed to such causes. However, they are also often caused by injuries - both internal and external - or illnesses. If the cause of acute pain is not resolved quickly, there is a risk that acute pain will turn into chronic pain. In addition, strong, persistent pain sensitizes the body to further pain. The nerves react "exaggerated" in the episode, even if the cause of the initial pain has already been eliminated. Whether a pain becomes chronic or not depends, among other things, on the patient's disposition, family environment and mental state.CBD has been shown to be effective against pain in several studies. The Cannabinoid combats several causes of pain, rather than simply suppressing the feeling of pain, the latter also belongs to the repertoire of cannabidiol.CBD fights painIn tissue injury, CBD increases the concentration of anandamide in the body. This occurs through the interaction of the cannabinoid with the receptors of the human endocannabinoid system. Ananadamide is an endogenous endocannabinoid that is directly produced by the body, which directly affects the pain. The more anandamide in the organism or around the injured area, the better the pain relief. Ananadamide binds to the CB1 receptor (cannabinoid-binding receptor) and to the TRPV1 (a vanilloid) receptor, where it immediately combats the pain. This finding was made by scientists in China in 2010, when they performed experiments on mice.CBD helps against inflammationInflammation is often the cause of pain. Inflamed tissue increases the number of free radicals. These are dangerous for the body, as they have, among other things, the property of damaging cells. CBD is an antioxidant. In this function, it has a similar effect to vitamins A, C and E: they trap free radicals and thus render them harmless.In addition, CBD also has an anti-inflammatory effect per se. For example, a study by GWPharmaceuticals showed that CBD's properties can help fight inflammatory conditions in the intestinal tract, rheumatoid arthritis, diabetes and nausea.Researchers at the University of Mississippi found that CBD reduces oxidative stress and helps fight inflammation. Many other studies - such as those of the scientists of the National Institutes of Health in Bethesda (USA) - all led to the same result: Cannabidiol inhibits inflammation. In Bethesda, researchers also confirmed that CBD works effectively against neuropathic pain. Neuropathic pain is caused by dysfunction or nerve injury and can sometimes be very severe.CBD protects the nervesCannabidiol not only works against neuropathic pain, but has been shown to protect against the death of nerve cells - such as ischemic stroke, traumatic brain injury, multiple sclerosis, Huntington's disease and other chronic nervous disorders. The neuroprotective (nerve-protective) effect of CBD has been demonstrated both in living organisms and in test tubes. Apparently, anandamide and 2-AG (2-arachidonylglycerol, another endocannabinoid) play an important role. In a traumatic brain injury, substances are released that can lead to secondary brain damage. In 2002 Mechoulem et al. Annanadamide and 2-AG can inhibit the action of harmful substances. The endocannabinoid system together with the cannabinoids thus takes over a protective function here. As described above, CBD contributes to the proliferation of anandamide in the body and thus protects the nerves. CBD relaxes the body and works against stressWhile the cannabinoid THC works primarily on the psyche, CBD has a relaxing and regulating effect on the body. Cannabidiol has an anticonvulsant effect, which is why it is sometimes used to combat epilepsy. Tense muscles often cause pain such as back, head, menstrual and other pains. But also CBD has positive effects on the psyche: It can be used well for the treatment of depression and schizophrenia. But it also helps against insomnia and stress. Stress is the cause of many pain disorders. Anyone who manages to reduce his stress often notices an accompanying pain relief. CBD combats the causesIn addition to inflammation, stress, tension and nerve disorders, CBD can be used against many other diseases. To name just a few:sleep disordersBurnoutanxiety disordersepilepsyschizophreniaNausea and vomitingDependence on addictive substancesParkinsonCrohn's diseasearthritisdifferent cancersspasticityasthmaCBD not only combats the pain as symptoms of disease, but acts - as a variety of different studies have revealed - against the causes themselves. For this reason alone, cannabidiol is likely to be a healthy alternative to the synthetic drugs of the pharmaceutical giants in the long term. These usually only suppress the pain. For the fight against causes additional medicines must be taken. Most painkillers and most prescription medicines, which are not natural but man-made, are harmful to the liver and kidneys - especially if taken over a long period of time. CBD, on the other hand, does not have a great health-endangering side-effect because it comes from nature and is very similar to human cannabinoids. Unfortunately, CBD research is still in its infancy. There are first drugs based on CBD. Overall, however, the science knows too little about the exact modes of action of cannabidiol. Questions such as "What helps CBD?" Could already be clarified well. But on the "How exactly does CBD?" There are only insufficient results. In the future, CBD is likely to play a bigger role in medicine - the current state of knowledge suggests strongly. Even though there are only very few CBD drugs worldwide so far, every human being in this country has the opportunity to treat themselves with CBD oil and other CBD products. CBD is not prescription, therefore legally available. For safety, always consult a doctor who is familiar with CBD. Application and dosage vary from person to person. In principle, with a little patience, everyone will find the right dose for themselves, as long as he starts small and slowly increases it until the desired effect begins. This makes CBD a good supplement to conventional pain therapy. With a bit of luck, some pain patients can even replace their existing funds with CBD altogether. A trial (under medical supervision) would be worth it. Source: SOMMER, Kathrin. Ob akut oder chronisch – CBD lindert Schmerzen.  13 Apr 2018 Dostupné z: https://www.hanf-magazin.com/medizin/cannabinoide/cbd-in-der-medizin/ob-akut-oder-chronisch-cbd-lindert-schmerzen/ Source photo: https://pixabay.com/cs/

Endogenous cannabinoids

Our organism, a criminal?The production of cannabis or the intoxicating tetrahydrocannabinol is prohibited in Germany, with exceptions. Our body forms endogenous cannabinoids. The anandamide discovered in 1992 is very similar to the THC. Is our organism a criminal? Does the mother behave irresponsibly when giving birth to her child, although breast milk contains endogenous cannabinoids? These questions simply remain unanswered and continue to focus on endogenous cannabinoids. Every higher living organism has an endocannabinoid system in which there are endogenous cannabinoids and cannabinoid receptors. These cannabinoid receptors can also dock with exogenous cannabinoids that are formed outside the body. However, cannabinoids formed in the body are called "endogenous". Endogenous is used within, exogenously outside of the body and as terms also in other areas of medicine. In 1992, the first endogenous cannabinoid was discovered with "anandamide", meanwhile also "2-arachidonylglycerol", "2-arachidonylglyceryl ether" and "O-arachidonylethanolamide" were discovered. There may be dozens of other endogenous cannabinoids that our body produces itself. These are messengers that dock to the cannabinoid receptors and trigger a reaction. Exogenous and endogenous cannabinoidsAmong the exogenous cannabinoids there are once the phytocannabinoids and the synthetic or semi-synthetic / artificial cannabinoids. The endogenous cannabinoids are always natural products as a product within our body. Here, however, as an organism, there are no great possibilities to form less or more of these endogenous cannabinoids, e.g. to achieve a more pleasant way of working. In the case of exogenous cannabinoids, however, it is possible to take them in any amount, if they are available in any quantity. Since marijuana always contains several cannabinoids at the same time, it would hardly be possible for normal users to take more of one cannabinoid without also including the other contained cannabinoids. However, if today's world wants it, then all of this would be possible because the cannabis strains can be optimized for breeding goals. On the other hand, the active ingredients can be extracted from the flowers as pure substances and then dosed very precisely. The difference in the bodyWhen exogenous cannabinoids are taken, they are taken up by the body via the lungs, the intestine, or the mucous membranes and pass into the bloodstream. This reaches the whole body and thus the effect of the exogenous cannabinoids also unfolds throughout the body. An exception would be only the external application of skin disorders. Endogenous cannabinoids, on the other hand, are always released where they are supposed to work. In the same body region where these agents or messengers arise, there are the matching cannabinoid receptors. As long as there are no messenger substances or they do not dock, the reaction of the receptors will be off, so they are so long inactive. However, if they are to react, the messenger substances are released to trigger a very targeted and spatially limited response. Delta-9-THC and anandamide are very similar in their effect. This THC is the only phytocannabinoid, which has an intoxicating effect and triggers the high. If anandamide is released in the organism, then only regionally. However, if you were to administer anandamide from the outside, it would go through the blood in the whole body and would certainly also make high. The name Anandamid was after all derived from Ananda, which means "bliss" and comes from the Sanskrit. Nevertheless, it can develop a very good medical effect in various diseases when THC is supplied to the organism. For the medical effect often enough dosages that do not make high, so that an everyday life remains possible. Difference between healthy and sickIn a healthy person, enough endogenous cannabinoids are released in different situations for the body to function normally. After all, cannabinoids are crucially important as messengers in the cannabinoid system, in order to control many different conscious and unconscious functions. In a sick person, there may be a deficiency in this cannabinoid system either at one or in some places. However, there may also be an additional need due to the disease. In both situations, it makes sense to take the right exogenous cannabinoids in sufficient quantities. In addition, of course, also be teased for pleasure. Or you simply take precautionary or relaxation CBD as well as other non-intoxicating cannabinoids. The healthy person can not do so much wrong, or would then usually stop by themselves quickly. In sick people, however, the difference in the effect is greater, which cannabinoids are taken in which concentration. Individual cannabinoids can be counterproductive in some diseases. Thus, too much THC can aggravate psychotic disorders quickly, but very often can be treated very well with CBD. While one can not exert much influence on the endogenous cannabinoids, as they are secreted by themselves in the body, exogenous cannabinoids can be used to great effect. That's exactly where the chances are in cannabinoid medicine. Source: BRUNGERT, Robert. Endogene Cannabinoide, 7 march 2018. Dostupné z: https://www.hanf-magazin.com/medizin/cannabinoide/endogene-cannabinoide/ Source photo: https://pixabay.com/cs/ 

Exogenous cannabinoids

Each vertebrate has a cannabinoid system and thus also forms endogenous cannabinoids. Phytocannabinoids have the highest number and highest concentration in the cannabis plant. Phytocannabinoids occur occasionally in other plants. This also applies to some endogenous cannabinoids. Thus, anandamide comes as an endogenous cannabinoid, e.g. in cocoa and thus in chocolate. Of course, the concentrations are not enough for an anandamide intoxication that would be similar to the THC noise. Flowing transitionsMany naturally occurring molecules can be replicated exactly in the chemistry lab. That would work for some endogenous cannabinoids and phytocannabinoids. So there may be cannabinoids that can be in two or maybe three of the three genotypes of cannabinoids. After all, anandamide is also found in cocoa and chocolate, and it may also be produced in the chemistry lab. However, the predominant place of origin is in our bodies, which would clearly make it one of the endogenous cannabinoids. Otherwise you would have to expand the term anandamide to the place of origin. In addition to identical molecules from nature, artificially mimicked molecules, which are almost identical, could potentially have the same effect as the naturally occurring cannabinoid. Nevertheless, the scientists would then choose two different names. After all, THC and anandamide have their own names. Flowing transitions include partially synthetically produced exogenous cannabinoids. Thus, due to the legal framework, some CBD-containing fiber hemp is cultivated to extract CBD, from which THC is subsequently produced. From an economic point of view, it would be much more useful to grow THC-containing cannabis directly. Technically, the atoms in the molecules of THC and CBD are arranged exactly the same. Only one double bond between the two molecules is different. If a natural product is merely adapted in the chemistry laboratory, then these are partly synthetic products. However, if the ingredients already come from the test tube or petroleum, then it would be a fully synthetic product. Partially synthetic cannabinoids are also referred to as artificial cannabinoids. They are neither pure natural product nor are they wholly derived from the chemistry lab. At least Dronabinol, with its active ingredient THC, is said to have a vegetable or partially synthetic origin, depending on the process. Hundreds of exogenous cannabinoidsCannabinoids have only recently entered the medical focus of the public. Once people only knew about THC, many now know that CBD is also a cannabinoid and there are many more cannabinoids. At the same time, since the spice wave, it has been publicly known that synthetic cannabinoids exist. Nevertheless, many do not understand the scope of this group of substances. If so far at least 113 pytocannabinoids have been identified among others only in the cannabis plant, there are probably already hundreds of synthetic cannabinoids. These are not discovered, but created. As already mentioned, in the molecule only one double bond has to be different, so that it becomes a different substance and has a completely different effect. That's why the synthetic cannabinoids are much more dangerous than the natural ones. If cannabis is spoken in Germany, then the proven cases invariably go back to synthetic cannabinoids. With natural cannabinoids it is hardly possible to reach a lethal dose in practical life. Furthermore, there are cannabinoids, in which the scientists are still arguing, whether they sort these molecules in the category of cannabinoids or not. Thus, the cannabis plant contains many terpenes, e.g. make out the smell and contribute to a medical effect. There are molecules that could easily be considered as terpenes and as exogenous cannabinoids, since they have the same properties for both substance classes. The differences between the cannabinoidsCannabinoids are messenger substances, also called neurotransmitters, which dock in the body to the cannabinoid receptors and thereby trigger a reaction. This triggered reaction is thus the effect of cannabinoids. Just as with other receptors, different messenger substances can dock differently or have different durations in the body. Some cannabinoids are metabolized faster or more slowly and thus have less or more time to dock to a cannabinoid receptor or other receptors. Each material can only dock to specific receptors and then occupy them. During docking, no other messenger can dock at this point. If counterproductive soil substances degrade only slowly in the body and dock very strongly and at the same time for a long time to a receptor, then one has to wait, so to speak longer, until a normal state can be set again. The period of time in which damage can occur is much longer. In the case of natural cannabinoids, these problems are manageable, since humanity has had experience with them for millennia. For synthetically produced exogenous cannabinoids, this is anything but manageable, since any late effects would be delayed by name. For consumers who jump into the cold water without experience or proper sources of information, the risk of critical overdose or unknown intolerance is far higher than with natural cannabinoids. Source: BRUNGERT, Robert. Exogene Cannabinoide, 18 march 2018 Dostupné z: https://www.hanf-magazin.com/medizin/cannabinoide/exogene-cannabinoide/ Source photo: https://pixabay.com/cs/ 

CBD in cosmetics - how well does cannabidiol affect our skin?

the biggest appeal features - no wonder we're ready to invest a lot in effective skin care products. Care products that contain CBD extracts such as CBD oil are currently emerging as a new trend in the cosmetics market. Are you just a marketing gimmick? On the contrary, medical studies hope that cannabidiol could help with skin problems: Which cosmetics with CBD are there?Almost the entire spectrum of personal care products you will also get today with CBD offset: from shampoo, on the lip balm to creams and ointments. The latter are advantageous because they are not washed out or washed off like soap, but let the valuable ingredients of the contained CBD extract penetrate into the skin. In addition to cannabidiol, ointments and creams naturally also contain ingredients which give the respective product its consistency and scent. Make sure that natural fats such as shea butter, mango butter or cocoa butter are used. They moisturize the skin and have a moisturizing effect. As fragrances, producers of high-quality products use natural essential oils, which in turn supply valuable terpenes. Quality products can be recognized by the fact that a CBD full spectrum extract forms the basis and neither artificial preservatives nor fragrances are processed. Vitamin E, on the other hand, is a natural preservative in CBD cosmetics that protects both our products and our skin from oxidation damage. Is CBD absorbed through the skin?Like all cannabinoids, CBD is a lipophilic substance that dissolves well in oils and fats. Therefore, it also combines with the human skin fat and is absorbed through the epidermis in the metabolism. Studies show that skin gives CBD 10 times more permeability than THC.  But can CBD also influence the organism through this passage? Preclinical experiments with animals show that CBD also has high efficacy via the transdermal route. For example, a gel containing cannabidiol in arthritic rats reduced joint swelling and pain and improved their mobility. In another experiment, CBD mitigated an addictive behavior induced by stress as an ointment in the experimental animals.  Also, pharmaceutical companies want to use the transdermal uptake of CBD in their products in the future: The Canadian manufacturer Cannabis Science announced to develop a CBD patch that will help patients with fibromyalgia and neuropathic pain in the future. How does CBD affect the skin? Because CBD is anti-inflammatory and immunoregulatory, it could primarily help people who suffer from inflammatory skin conditions. Researchers see above all possibilities in the treatment of acne. Because of the activation of the vanilloid receptor type 4 CBD demonstrably inhibits the activity of the sebaceous cells in the sebaceous glands, called sebocytes.  In addition, it also has an inhibitory effect on cells of the epidermis, which are responsible for the formation of the horny layer. This could help people with psoriasis, whose complaints are caused by excessive activity of horn-forming keratinocytes. Finally, patients with severe skin diseases already benefit from CBD in practice. Case reports of sufferers of rare skin conditions, such as epidermolysis bullosa, show that their symptoms significantly decreased with cannabidiol therapy. Itching, sore and scarring, blisters and the limitations of mobility decreased so much that some patients could even do without opioid analgesics.  Source: CBD in Kosmetik – wie gut wirkt Cannabidiol auf unsere Haut? Apr 25,2019. Dostupné z: https://fivebloom.de/blogs/cbd-news/cbd-kosmetik Source photo: https://pixabay.com/cs/

CBD in allergies - can cannabidiol soothe the immune system?

Some of them are happy when trees and flowers are blooming in spring, while others would rather escape to the North Pole. In particular, hay fever sufferers can hardly enjoy the warm season, because they bring along with the pollen Schniefnasen, watery eyes and sneezing attacks. But also food allergies; House dust allergies and incompatibilities with chemicals make everyday life difficult for those affected. What happens in the body during allergies, such as CBD oil could increase the well-being of allergy sufferers, you will find out here: What are allergies?In an allergy, the human organism reacts to individual substances of its environment (allergens) with a strong immune response. In this case, pro-inflammatory substances such as e.g. Released histamine that cause typical discomfort. The physical symptoms then express themselves in:red and irritated eyesirritated nasal mucosahay feverSneezeto coughallergic asthmadigestive problemsSkin irritation and rashEczema and eczemaFor example, allergens are taken via the respiratory tract, as is the case with widespread hay fever. According to recent surveys, about 14.5 percent of all Germans suffer from respiratory ailments during their heyday. In addition, allergens can also enter the body through food or through direct skin contact. What is the usual therapy for allergies?Here are two approaches: The first is based on drugs that reduce the production of the inflammatory histamine in the body, so-called antihistamines. These preparations are effective and are available over the counter. However, they are sometimes associated with unpleasant side effects, especially with severe fatigue. In addition, there is the possibility of hyposensitization for allergy sufferers. In this case, the person concerned receives low-dose injections of the corresponding allergen, in order to slowly get the body used to the substance. How does CBD affect our immune system? The human endocannabinoid system and the immune system are closely related. After all, CB2 receptors to which cannabinode can bind are located on the important cells of the immune system, for example the T cells. Here, cannabinoids can regulate how many pro-inflammatory signaling substances are released during an immune response. Researchers in the animal model of asthma demonstrated that this regulatory effect can have a beneficial effect on allergic reactions. Treatment with CBD was able to significantly reduce the pro-inflammatory signaling, various interleukins and tumor necrosis factor alpha in the lung tissue of the experimental animals. The authors of the study are in favor of CBD as a potential future therapeutic for the inflammatory processes in asthma. Surveys in dermatology, however, see opportunities in CBD to treat atopic dermatitis and contact allergies. Finally, scientists in the animal model of arthritis have observed that cannabidiol can also regulate autoimmune responses by reducing the presence of proinflammatory signaling in the synovial fluid.  Which CBD products are suitable for an allergy?Dietary supplements with CBD are freely available in Germany and do not bring the risk of side effects. Unlike with the use of antihistamines, allergy sufferers do not have to worry about drowsiness. It is known from scientific experiments that CBD is absorbed well via the oral mucosa and via the transdermal route. In principle, allergy sufferers can therefore use CBD oil or CBD balm. When products are applied to the skin, it is important that there are no ingredients that can cause allergies. Ideal are CBD balms, which contain only natural fats such as shea butter or mango butter and do without chemical preservatives and fragrances. Even less risk of allergies exists in CBD oils based on MCT oils. They are dripped under the tongue on the oral mucosa to ensure optimal absorption of the ingredients in the organism. Beginners should begin with a 5 to 10 percent CBD oil picking and a dosage of 3 drops twice a day. Source: CBD bei Allergien – kann Cannabidiol das Immunsystem beruhigen?  May 2, 2019. Dostupné z: https://fivebloom.de/blogs/cbd-news/cbd-bei-allergien-oder-heuschnupfen Source photo: https://pixabay.com/cs/

Regular pain: CBD helps

CBD relaxes and relieves crampsWhile most of the average 28-day cycle is relatively calm and normal, the uterine muscles begin to contract just before the menstrual period. These contractions interrupt blood flow in the abdomen. It is precisely this interruption that causes more pain in one woman and less pain in the other. Happy are those who do not suffer at all. In some girls and women, however, the pain is so unbearable that they therefore even fail in everyday life, so must report to the employer sick or can not go to sports. In Germany, therefore, many patients resort to analgesics such as ibuprofen or acetaminophen. Others prefer to take antispasmodic drugs from the pharmacy. However, this is more of a permanent solution with two eyes closed, as this type of medication has negative effects on the body. For example, they strain the kidneys when taken regularly. Some pain sufferers now stick electrodes instead to the skin. By light surges, the muscles should relax and provide relief. While some swear by it, others complain about the annoying feeling of having to walk around the bikini area with electrode stickers, where one can not move quite as freely during the days anyway. Often, young women are prescribed the pill to prevent the unpleasant side effects of menstruation. However, it is artificially intervened in the hormone balance to prevent ovulation. The cannabinoid CBD is according to the current state of research free of side effects. It naturally acts on the human endocannabinoid system. This expands throughout the body and even produces various cannabinoids to keep the immune system intact. However, this system is prone to disorders such as illness and stress - the latter is also caused by pain. By administering CBD in the form of oil or capsules, the inner balance can be restored. CBD has a relaxing, anti-spasmodic and anti-inflammatory effect. For menstrual problems, it is therefore a good treatment option. Since it contains virtually no THC and therefore does not have an intoxicating effect, women who suffer from period pain can obtain CBD legally and without a prescription. Different types of menstrual pain and their causes The female cycle is determined by different hormones. The goal is to prepare the body for possible reproduction. Therefore, the uterine lining builds up in the first half of the cycle. It is well supplied with blood and thick or short: ready for the implantation of the fertilized egg. However, if there is no fertilization and thus no pregnancy, the mucosa dissolves in the second half of the cycle after ovulation from the uterus. The excretion takes place during the period. After the menstrual period, the circulation starts again, so the menstrual pain occurs every month again. Generally, a distinction is made between primary and secondary menstrual pain. The primary menstrual pain falls into the category of "natural", which is pain that occurs during the menstrual period, without any pathological change in the female body. The women who suffer from primary periodic pain have been fighting this problem since puberty. Secondary menstrual pain primarily affects older women and is mostly due to illness. Changes in the female reproductive system often cause painful days. Such changes include, for example, endometriosis (small, benign growths in the abdomen), uterine infections, and ovarian cysts. Frequently by these diseases not only the intensity of bleeding increases, but also pain. In general, there are various factors, besides malformations or diseases, which can aggravate menstrual pain. These include a low body weight, an irregular or longer than average cycle, the consumption of alcohol and nicotine, the prevention of pregnancy with the help of the spiral, stress or other psychological causes. Symptoms of menstrual painMany readers know her too well - the typical symptoms of menstrual cramps: cramping and tearing in the abdomen. The pain can follow at short intervals, be regular or prolonged, and can be up to the back. Often, digestion is also affected during the period, so some women suffer from diarrhea or nausea. Even headaches can be part of the discomfort. Anyone who is in constant pain and uncomfortable will eventually get into a bad mood. In addition, fatigue, fatigue and lower concentration or performance are added to this. Many women would therefore just like to lie in the hot tub or with a hot water bottle on the stomach on the couch and wait for the first two, so the worst days, pass as quickly as possible. Different forms of CBD for menstrual pain Not only hot baths and hot water bottles relax the cramped uterus, but also sex. But after a suitable partner is not always and everywhere available and women can not spend hours in the bathroom, it makes sense to relax the body in other ways. CBD has anti-spasmodic properties, reduces stress and relaxes, and therefore relieves menstrual pain. Already Queen Victoria's doctor, Sir Joshua Reynolds, knew about the beneficial effects of the cannabis plant and ordered the majesty a suitable cannabis tincture against her menstrual pain. Women in Asia and Africa have also been relying on natural pain relief from cannabis products for centuries. In our society, the use and research of cannabinoids has long been neglected by the illegalization of the hemp plant. However, countries such as the US and Canada are now turning around and the research and production of various cannabis products is evidently progressing inexorably. Europe is slowly catching up. The US actress Whoopi Goldberg has recognized the trend and together with the food manufacturer Maya Elisabeth sells medical cannabis products under the name "whoopi & maya", which are tailored to women with regular pains. In addition to cannabis tinctures and ointments, the ladies also offer a bath additive and chocolate with the corresponding active ingredients. In liberal California and the US state of Colorado, pain-stricken women enjoy the so-called cannabis tampons, which are marketed under the name of Foria Relief. Actually, this product is not really a tampon, but a suppository, which is introduced before using a tampon. Within 15 to 30 minutes, the suppository dissolves, so that the active ingredients are absorbed by the vaginal mucosa. In Germany, the suppositories are not yet available because they contain besides ten milligrams of legal CBD also 60 milligrams of psychoactive THC. Many women reported having a relaxing effect and pain relief after about eight minutes. The THC can be detected by the usual drug tests in the body. Medically sound studies on Foria Relief are pending. We also have medical cannabis products on prescription from the pharmacy. These are mainly used in palliative medicine. In menstrual pain, it would be extremely difficult to find a doctor and a health insurance company who would participate in a prescription. The legal alternative is CBD. In the form of oil, you can either take cannabidiol orally or drip one or two drops on a tampon to make it easier to get it right where it's needed. Instructions for buying CBD productsTo minimize the unwanted ingestion of any pollutants, attention should be paid to the bio-seal when purchasing CBD products. Oils should contain at least 99 percent pure CBD. When manufacturing, it is important to keep an eye on ensuring that the products are as close as possible to the GMP (Good Manufacturing Practice for Medicines) and ISO standards so that they are of a certain quality. Court decision regarding cannabis use against menstrual painAt this point the readers should not be deprived of the court order of 4 January 2017 from Baden-Württemberg: A woman who regularly consumed cannabis for six to seven days a month - the intoxicating THC variant, not the pure CBD - wanted to deprive the driving license authority of their driving license. In an urgent procedure, however, the Freiburg administrative court ruled that the woman was allowed to keep her driver's license for the time being. The reasoning was that the person concerned would firstly have not combined consumption and driving, and secondly, they would not take cannabis regularly. Even if the consumption was monthly over several days, the woman did not take THC-containing products on the menstruation-free days and therefore did not fulfill the conditions necessary for a driving license withdrawal.The decision may be understood as a positive sign in the direction of cannabis for pain relief. Source: SOMMER, Kathryn. Regelschmerzen: CBD schafft Abhilfe. 21 Feb, 2018 Dostupné z: https://www.hanf-magazin.com/medizin/cannabinoide/cbd-in-der-medizin/regelschmerzen-cbd-schafft-abhilfe/ Source photo: https://pixabay.com/cs/

Cannabis for autistic children

MODI'IN IN ISRAEL - Noa Shulman, 17 years old, is one of those children who have already attracted attention as an ego-centrist in kindergarten and at school. She lives seemingly completely withdrawn in her very own universe and has a hard time communicating with the outside world: Noa suffers from autism.When Noa comes home from school, she is spoon fed by her mother, Yael - sweet potato puree mixed with a cannabis-derived oil. Noa is part of the first clinical trial in the world to demonstrate the benefits of medical marijuana in the treatment of adolescents with autism. The positive effect should be provenThis study could be the breakthrough, helping millions of sufferers and their parents help and alleviate symptoms. The study started in January of this year at the Shaare Zedek Medical Center in Jerusalem. 120 children and young adults aged 5 to 29 with mild and severe autistic features are participating in the study, which will end in 2018. The group is expected to take cannabis daily, planned twice twelve weeks, interrupted by a one-month break. Nobody smokes a joint though. An extract of cannabidiol, which is mixed in the ratio of 20 to 1 with olive oil, is administered.There has long been evidence that cannabidiol (CBD) helps children and adolescents such as Noa, as has no other treatment or medication. This study should prove that. In 1992, Israel was the first country in the world to approve the use of medical marijuana. Like Canada and the Netherlands, this medical program is supported by the state and paid by the government. Tamir Gedo, CEO of "Breath of Life Pharma *," who made the cannabis oil for study participants, said that a mother told him, "My child is talking uninterruptedly. ... He never said a word before. And he is twelve years old. "Of course, there are also external concerns about the study. Pediatricians from America fear damage to the participants' brains due to the early intake of cannabis. But Gedo sees it differently, other drugs such as opioids hurt the children much more. "These families have no other hope." In Germany, the number of autistic people is estimated at around 35,000. * "Breath of Life Pharma" (BOL Pharma) is led by an experienced team of medical experts, scientists and cannabis business experts who have vast experience in clinical trials, precision farming, agriculture and marketing of pharmaceutical and healthcare products. BOL Pharma also owns the largest cannabis plantation in Israel, which is used for medical purposes. Her specialties include immunology (multiple sclerosis, fibromyalgia), pain therapy (chronic pain, neurological pain), gastrointestinal diseases (IBD), rheumatology (osteoarthritis), dermatology (psoriasis, atopic dermatitis). Source: NESTLER, Julia. Cannabis für autistische Kinder. 5 Jun 2017. Dostupné z: https://www.hanf-magazin.com/medizin/cannabinoide/cbd-in-der-medizin/cannabis-fuer-autistische-kinder/ Source photo: https://pixabay.com/cs/

Cannabis products for external use

We now know that the use of cannabis has health benefits. We can treat bowel disease with cannabis, fight colon cancer or relieve spasmodic symptoms. In addition, the effect of cannabis is also applicable to a great many other ailments, but the effects have not been completely investigated. Whether one eventually smokes or otherwise consumes the grass is up to the consumer.If you do not want to smoke, you can inject it through the skin, in the form of oil, through the food, or in finished foods. The possibilities are more or less open to us. A first step has already been taken with the legalization by prescription, even if it is only really recognized and serious diseases. The normal migraine patient will hardly get legal cannabis. That's a pity, but maybe that will change. Today, however, we are enriching ourselves with yet another effect of cannabis, namely the positive effects on our skin. The products are largely legally available.Effectiveness of THC and CBD confirmedClinical trials and numerous laboratory tests have now confirmed the efficacy of cannabis ingredients. It was investigated to what extent cannabis products can help against skin redness, inflammation, psoriasis, open wounds, acne or other skin diseases. Of course, the cannabis does not need to be smoked, but can be purchased legally in lotions, balms, oils or patches. We are looking forward to a product test in this regard and hope to be able to say more about exact products soon.Actually, people knew back in antiquity that cannabis and certain plant components help against skin diseases. For this reason, cannabis was mixed with other plants, herbs or animal extracts and prepared ointments. In today's laboratory tests, the effect was confirmed, because the cannabinoids increase the biochemical defenses of the skin. Unfortunately, we can not say much about exactly how cannabinoids do this and stimulate the healing process, because unfortunately research is not yet far enough. But the fact is that it helps and acts against a disease infestation of the skin.Acne and skin irritations - effects and resultsCannabinoids can reduce and even completely combat inflammation in the skin's sebaceous glands. Skin glands ensure that the skin is coated with sufficient natural fats. If the glands produce too much sebum, skin disorders or acne often occur. Cannabinoids have been proven to help against acne, eczema and other skin disorders. And again it was the mice that proved these theories. However, it is not just the cannabinoids that are good for our skin. The extracts of cannabis seeds, for example, reduced skin redness of subjects. These seeds contain proteins, oils and antioxidants to help against pimples.Skin care products are experiencing an upswingCannabis-enriched lotions are increasingly being sold and more and more people are experiencing the beneficial effects. Balsams, oils, gels or transdermal patches containing CBD, THC or terpene can be purchased. The cannabis preparations contain various substances, so that the skin can absorb the essential ingredients well. For example, the creams contain certain herbs to actively ensure intake. The products can be applied directly to the inflamed area and locally controlled.Will not you get high on it?No, because the ointments do not reach the bloodstream or the nervous system, whereby no high-effect can be experienced. The contained cannabinoids can bind with the CB2 receptors and act on the peripheral level.-> If you like, you can make your own CBD ointment yourself. All you need is cutaways, stalks and a few small buds. These are enriched with coconut oil and beeswax. We will work out a more exact recipe and of course publish it. Dermatitis and psoriasis are the perfect areas of application and you will see fast results. But even with sore muscles or against arthritis and for other pain relief help the homemade ointments.Patients and doctors should go new waysThe experiences of physicians and patients are becoming more and more frequent and also various official studies are proving more and more the positive effects on different processes. Relieving skin problems could be a breakthrough for cannabis products. In the US, various cannabis products are already being used to relieve symptoms such as fibromyalgia, ALS, sunburn, open wounds or migraine. The modes of action are antibacterial and anti-inflammatory, the properties of cannabis there are widely recognized. What works there can not be wrong here, right?Found a new drug?Now another active substance is to be held responsible for the positive effects on our organism, namely the so-called CBG. An active ingredient that can help against acne and skin aging.Of course, we must point out here that cannabis is not a panacea and you should always discuss your treatment with a doctor. At least you could ask in advance if self treatment with various cannabis products makes sense. Source: DIRSCHL, Jenny. Cannabisprodukte zur äußeren Anwendung. 17 feb, 2017. Dostupné z: https://www.hanf-magazin.com/medizin/cannabinoide/thc/cannabisprodukte-zur-aeusseren-anwendung/Source photo: https://pixabay.com/cs/

CBD (cannabidiol) in ancient Egypt

Often, cannabidiol is reported as a new phenomenon. Due to the growing cultural acceptance of the hemp plant, CBD has experienced a tremendous increase in popularity over the last decade. In fact, the cannabinoid was used much earlier by one of the Earth's oldest civilizations - Ancient Egypt.Cannabidiol - a wonder drug?CBD is a phytocannabinoid - a natural, plant-produced compound. In this case, the compound comes from the hemp plant. In 1964, the Israeli scientist Dr. Raphael Mechoulam the psychoactive substance THC. The now 88-year-old Professor of Pharmaceutical Chemistry and Natural Products at the Hebrew University of Jerusalem is recognized as one of the most important researchers in cannabis research by discovering the most important ingredients of the cannabis plant. In addition, it has played a significant role in Israel's pioneering role in researching the therapeutic properties of cannabinoids and in medical applications.For example, by altering the concentration of neurotransmitters in the brain, the effect of cannabidiol can affect pain, contribute to relaxation, or help with sleep problems. There are reports of the anti-inflammatory effect of topical treatment of inflammatory skin diseases such as atopic dermatitis.originCBD is made from the hemp plant that has been cultivated by humans for thousands of years for its versatile fibers, seeds and flowers. The oldest finds come from China around 2800 BC. Chr., Where one manufactured ropes from hemp fibers.Presumably, however, the plant has been used earlier and there is evidence of its use in traditional Chinese medicine, which continues to decline. Over time, the hemp plant in the paper, textile, food and medical industries became more important worldwide, until the cultivation of hemp was taxed so heavily in the US in 1937 with the Marijuana Tax Act that it was barely affordable for farmers more rewarded.Holy hempSeshat was an ancient Egyptian deity of wisdom, writing and knowledge. She was seen as a writer and mathematician. The deity depicted as a woman often wore a panther skin a staff and a headband, over which a green star is depicted, which many researchers interpret as hemp bloom.The Ebers Papyrus is a medical script from Ancient Egypt. It is one of the oldest surviving texts and contains texts on medical topics with a wide range of descriptions of diseases and their symptoms and diagnoses. In addition, the papyrus contains tips for the treatment of various ailments and the preparation of remedies.The uses of cannabis for medical purposes recorded there date from 1700 BC. Various texts describe the application and preparation of several cannabis recipes. Thus, tinctures of cannabis and other herbs and plants to help with glaucoma, relieve nail problems or help in the form of vaginal suppositories from cannabis and honey at birth. Also in the coffins of mummies researchers found remains of the hemp plant, which were given to the person as an important tool on the journey.Cannabis from EgyptWhen Napoleon besieged Egypt during the Egyptian expedition from 1798 to 1801, French soldiers came into contact with hashish. It is believed that they took the hashish to Europe, which made it well known and appreciated.Although cannabis is illegal in Egypt and consumption and cultivation are severely punished, the historical significance and use of beneficial and medicinal plants suggest that hemp has played an important role in ancient Egypt. Perhaps the increasing research into medicinal properties can help bring hemp back to the center of society.Source: BOEDEFELD, Christian. CBD (Cannabidiol) im alten Ägypten.28 Mai, 2019. Dostupné z: https://www.hanf-magazin.com/medizin/cannabismedizin-allgemein/cbd-cannabidiol-im-alten-aegypten/ Source photo: https://pixabay.com/cs/